Jasplakinolide

Jasplakinolide is a natural cyclic peptide that acts as a potent actin polymerization agent. It is derived from marine sponge species such as Jaspis johnstoni and other similar sponges. Jasplakinolide stabilizes actin filaments and promotes their assembly, which makes it a valuable tool for studying the dynamics of the actin cytoskeleton in various cellular processes.

Alfa Chemistry provides high-quality jasplakinolide and related product customization services.

Product Detail

Product Name	Jasplakinolide
CAS No.	102396-24-7
Catalog	ALKS102396247
Purity	≥ 99%
Appearance	White to off-white solid
Molecular Weight	709.67
Molecular Formula	C36H45BrN4O6
Structure Classification	Cyclopeptides
Solubility	DMSO: 10 mg/mL (14.09 mM; Need ultrasonic and warming)
Storage	Sealed storage, away from moisture

Applications of Jasplakinolide

Cell Biology Research

Jasplakinolide is widely used in cell biology to study the dynamics of the actin cytoskeleton. By stabilizing actin filaments, it allows researchers to investigate the roles of actin in various cellular processes, including motility, shape maintenance, and division.

Cancer Research

Jasplakinolide has shown potential anticancer activity by inducing apoptosis (programmed cell death) in cancer cells. Its ability to disrupt the actin cytoskeleton can lead to cell death in rapidly dividing cancer cells, making it a subject of interest for developing novel anticancer therapies.

Pharmacological Studies

The unique mechanism of action of jasplakinolide makes it a valuable tool for developing new drugs targeting the cytoskeleton. Its structure and function provide insights into designing analogs or derivatives with improved therapeutic properties.

Neuronal Studies

It is used to study the role of actin dynamics in neuronal development and function. By stabilizing actin filaments, researchers can explore how changes in the cytoskeleton affect neuronal growth, synapse formation, and plasticity.

Choose Alfa Chemistry

At Alfa Chemistry, we pride ourselves on delivering high-quality jasplakinolide products tailored to meet your unique needs. Our dedication to excellence ensures that our jasplakinolide solutions are crafted with the highest standards in mind. We offer comprehensive customization services to precisely match your specific requirements, ensuring optimal results. Contact us today to learn more and experience the exceptional quality we bring to the table.