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Nuciferine is an aporphine alkaloid first isolated from Nelumbo nucifera Gaertn as the main bioactive ingredient. Additionally, it was also obtained from some other plants. Nuciferine has been shown to stimulate insulin secretion by binding to sulfonylurea receptor, then increasing intracellular calcium and stimulating cAMP responsive pathway. Nuciferine was also found to reduce the development of atherosclerosis via inhibition of vascular smooth muscle cell proliferation and migration. The multiple biological properties of nuciferine, including anti-hyperlipidemic, anti-obesity, anti-fatty liver, antidiabetic, anti-hyperuricemic, antitumor, anti-inflammatory, antiviral, and antioxidant activity, have contributed to its rapid development in the pharmaceutical industry.
Figure 1. The chemical structure of nuciferine.
The advent of nuciferine has provided much inspiration for the discovery of innovative drugs. The detection of nuciferine in samples has become a popular service through professional technical means. Alfa Chemistry's detection platform uses techniques such as HPLC and GC-MS to efficiently and accurately detect changes in the content of nuciferine. Our services include but are not limited to the following.
Our detection platforms include but are not limited to the following.
Alfa Chemistry is a company specializing in the development and research of alkaloids. We have highly experienced experts and trusted detection platforms. We ensure the highest quality detection services for our customers.
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