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Catalog Number | ACM86639625 |
CAS Number | 86639-62-5 |
Structure | ![]() |
Synonyms | 4α-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione |
Molecular Weight | 393.35 |
Purity | 95%+ |
PhysicalState | Powder |
What is the chemical formula of 10-Nitrocamptothecin?
The chemical formula of 10-Nitrocamptothecin is C20H15N3O6.
What is the molecular weight of 10-Nitrocamptothecin?
The molecular weight of 10-Nitrocamptothecin is 393.35.
What is the boiling point of 10-Nitrocamptothecin?
The boiling point of 10-Nitrocamptothecin is predicted to be 827.4±65.0 °C.
What is the density of 10-Nitrocamptothecin?
The density of 10-Nitrocamptothecin is predicted to be 1.63±0.1 g/cm3.
What is the pKa value of 10-Nitrocamptothecin?
The pKa value of 10-Nitrocamptothecin is predicted to be 11.17±0.20.
What are the synonyms of 10-Nitrocamptothecin?
The synonyms of 10-Nitrocamptothecin include RUBETICAN, CAMPTOTHECIN, 9-NITRO-20(S)-, 9-NITRO-CPT, and more.
What are the usage and synthesis of 10-Nitrocamptothecin?
10-Nitrocamptothecin can induce apoptosis, delay cell growth in S phase and G2M phase, inhibit cell cycle throughout, and is dose- and time-dependent.
What is the role of Rubitecan, which is a prodrug for 9-aminocamptothecin?
Rubitecan is an antineoplastic agent, an EC 5.99.1.2 (DNA topoisomerase) inhibitor, and a prodrug.
What type of compound is 10-Nitrocamptothecin classified as?
10-Nitrocamptothecin is classified as a pyranoindolizinoquinoline, a C-nitro compound, a semisynthetic derivative, a tertiary alcohol, and a delta-lactone.
How does 10-Nitrocamptothecin affect cell division?
10-Nitrocamptothecin delays S phase and G2M phase of cell growth, induces apoptosis, and inhibits cell cycle throughout in a dose- and time-dependent manner.
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