Aaptamine

Catalog Number	ACM85547224-1
CAS Number	85547-22-4
Description	Aaptamine is a spongean alkaloid isolated from a sea sponge Aaptos aaptos.
Synonyms	8,9-Dimethoxy-1H-benzo[de][1,6]naphthyridine
IUPAC Name	11,12-Dimethoxy-2,6-diazatricyclo[7.3.1.05,13]trideca-1,3,5(13),7,9,11-hexaene
Molecular Weight	228.25
Canonical SMILES	COC1=C(C2=NC=CC3=C2C(=C1)C=CN3)OC
InChI	InChI=1S/C13H12N2O2/c1-16-10-7-8-3-5-14-9-4-6-15-12(11(8)9)13(10)17-2/h3-7,14H,1-2H3
InChI Key	UERYGOYPBXIFQV-UHFFFAOYSA-N
Purity	95%+
Complexity	308
Covalently-Bonded Unit Count	1
Defined Atom Stereocenter Count	0
Exact Mass	228.08987763
Heavy Atom Count	17
Hydrogen Bond Acceptor Count	4
Hydrogen Bond Donor Count	1
Monoisotopic Mass	228.08987763
PhysicalState	Powder
Rotatable Bond Count	2
Topological Polar Surface Area	43.4 Ų

Custom Q&A

What is the chemical name of the compound being referred to in the document?

8,9-DIMETHOXY-1H-BENZO[DE][1,6]NAPHTHYRIDINE

What are some synonyms of Aaptamine?

AAPTAMINE, Apatamine, 1H-Benzo[de][1,6]naphthyridine

What is the CAS number of Aaptamine?

CAS: 85547-22-4

What is the molecular formula of Aaptamine?

MF: C13H12N2O2

What is the molecular weight of Aaptamine?

MW: 228.25

How should Aaptamine be stored?

storage temp: 4°C, protect from light

In which solvents is Aaptamine soluble?

Solubility: DMSO (soluble), Ethanol (soluble)

What are the uses of Aaptamine?

Aaptamine can activate the p21 promoter in the absence of p53 and can function as a proteasome inhibitor.

Where can the synthesis of Aaptamine be found?

Synthesis Reference(s): The Journal of Organic Chemistry, 52, p. 616, 1987 and Tetrahedron Letters, 31, p. 569, 1990

What is the DOI for the synthesis of Aaptamine in The Journal of Organic Chemistry?

DOI: 10.1021/jo00380a024

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