Cinchonine hydrochloride

Catalog Number	ACM5949111
CAS Number	5949-11-1
Structure
Synonyms	Cinchonan-9(S)-ol monohydrochloride
Molecular Weight	330.8
Molecular Formula	C19H22N2O.HCl
InChI	InChI=1S/C19H22N2O.ClH/c1-2-13-12-21-10-8-14(13)11-18(21)19(22)16-7-9-20-17-6-4-3-5-15(16)17;/h2-7,9,13-14,18-19,22H,1,8,10-12H2;1H/t13-,14-,18+,19-;/m0./s1
InChI Key	IMUHWLVEEVGMBC-BKUXTCEESA-N
Melting Point	208-218 °C
Purity	98%+
Appearance	crystals
Complexity	412
Covalently-Bonded Unit Count	2
Defined Atom Stereocenter Count	4
Exact Mass	330.1498911
Heavy Atom Count	23
Hydrogen Bond Acceptor Count	3
Hydrogen Bond Donor Count	2
Isomeric SMILES	C=C[C@H]1CN2CC[C@H]1C[C@@H]2[C@H](C3=CC=NC4=CC=CC=C34)O.Cl
Monoisotopic Mass	330.1498911
PhysicalState	Solid
Rotatable Bond Count	3
Topological Polar Surface Area	36.4 Ų

Custom Q&A

What is the chemical formula of Cinchonine hydrochloride?

The chemical formula of Cinchonine hydrochloride is C19H23ClN2O.

What is the molecular weight of Cinchonine hydrochloride?

The molecular weight of Cinchonine hydrochloride is 330.85.

What is the melting point of Cinchonine hydrochloride?

The melting point of Cinchonine hydrochloride is 208-218 °C.

How should Cinchonine hydrochloride be stored?

Cinchonine hydrochloride should be stored under inert gas (nitrogen or Argon) at 2-8°C.

What are the hazard codes associated with Cinchonine hydrochloride?

The hazard codes associated with Cinchonine hydrochloride are Xn,Xi.

How is Cinchonine hydrochloride used in pharmaceutical formulations?

Cinchonine hydrochloride possesses the required solubility and bioavailability for pharmaceutical formulations while retaining desired therapeutic properties.

In what ways is Cinchonine hydrochloride stable in solution?

Cinchonine hydrochloride is stable in solution, which facilitates the preparation of aqueous formulations, especially injections.

How is Cinchonine hydrochloride used in the treatment of cancer-related diseases?

Cinchonine hydrochloride compositions are useful in the treatment of cancer-related diseases with "multidrug resistance" (MDR) phenomena.

What biological activity does Cinchonine hydrochloride have?

Cinchonine hydrochloride is a natural compound in cinchona bark with antimalarial activity. It can activate endoplasmic reticulum stress to induce apoptosis in human hepatoma cells.

What are the safety statements associated with Cinchonine hydrochloride?

The safety statements associated with Cinchonine hydrochloride are 36/37-36-26.

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