Copanlisib

Catalog Number	ACM1032568630
CAS Number	1032568-63-0
Synonyms	Aliqopa
IUPAC Name	2-Amino-N-[7-methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydro-1H-imidazo[1,2-c]quinazolin-5-ylidene]pyrimidine-5-carboxamide
Molecular Weight	480.52
Molecular Formula	C23H28N8O4
Canonical SMILES	COC1=C(C=CC2=C3NCCN3C(=NC(=O)C4=CN=C(N=C4)N)N=C21)OCCCN5CCOCC5
InChI	InChI=1S/C23H28N8O4/c1-33-19-17(35-10-2-6-30-8-11-34-12-9-30)4-3-16-18(19)28-23(31-7-5-25-20(16)31)29-21(32)15-13-26-22(24)27-14-15/h3-4,13-14,25H,2,5-12H2,1H3,(H2,24,26,27)
InChI Key	MWYDSXOGIBMAET-UHFFFAOYSA-N
Purity	98%+
Storage	Store in dry, low temperature, sealed, 2-8 °C.
Complexity	974
Exact Mass	480.22335140
Heavy Atom Count	35
Monoisotopic Mass	480.22335140
Topological Polar Surface Area	140Ų

Custom Q&A

What is the chemical formula of Copanlisib?

The chemical formula of Copanlisib is C23H28N8O4.

What is the molecular weight of Copanlisib?

The molecular weight of Copanlisib is 480.52.

What are some synonyms for BAY 80-6946 (Copanlisib)?

Some synonyms for Copanlisib include BAY80-6946, Copanlisib(BAY80-6946), and 2-Amino-N-[2,3-dihydro-7-methoxy-8-[3-(4-morpholinyl)propoxy]imidazo[1,2-c]quinazolin-5-yl]-5-pyrimidinecarboxamide.

What is the storage temperature recommended for Copanlisib?

The recommended storage temperature for Copanlisib is -20°C.

What is the solubility of Copanlisib in DMSO, water, and ethanol?

Copanlisib is insoluble in DMSO, water, and ethanol.

What is the density of Copanlisib?

The density of Copanlisib is 1.51.

What are the main uses of BAY 80-6946 (Copanlisib)?

BAY 80-6946 is a highly selective intravenous PI3K inhibitor with potent p110α and p110δ activities in tumor cell lines and xenograft models.

What is the role of Copanlisib in the treatment of relapsed follicular lymphoma?

Copanlisib is used for the treatment of relapsed follicular lymphoma in patients who have received at least 2 prior systemic therapies.

What type of inhibitor is Copanlisib?

Copanlisib is an intravenous pan-class I PI3K inhibitor.

What are some of the chemical properties of Copanlisib?

Some chemical properties of Copanlisib include being a solid form, a pka value of 8.42, and being insoluble in various solvents.

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