Corytuberine

Catalog Number	ACM517566-1
CAS Number	517-56-6
Structure
Description	Corytuberine is a bisbenzylisoquinoline alkaloid that has shown low bioavailability and significant toxicity in animal studies. It is found in a traditional Chinese herb known as Corydalis, which has been used to treat pain, inflammation, and convulsions. The mechanism of action of corytuberine is not well understood but it may be due to the inhibition of prostaglandin synthesis. This alkaloid may also have antinociceptive properties. There are many natural compounds present in Corydalis including protocatechuic acid and protopine. Protocatechuic acid is an antioxidant that can inhibit the reaction between lipoxygenase and arachidonic acid, while protopine can bind to DNA and prevent transcription. Other metabolites include cryptopine, fatty acids, and cell nuclei.
Synonyms	(6aS)-5,6,6a,7-Tetrahydro-2,10-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline-1,11-diol2,10-Dimethoxy-6a-a-aporphine-1,11-diol(+)-Co rytuberine
IUPAC Name	(6aS)-2,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quin...
Molecular Weight	327.37 g/mol
Molecular Formula	C19H21NO4
Canonical SMILES	CN1CCC2=CC(=C(C3=C2[C@@H]1CC4=C3C(=C(C=C4)OC)O)O)OC
InChI	InChI=1S/C19H21NO4/c1-20-7-6-11-9-14(24-3)19(22)17-15(11)12(20)8-10-4-5-13(23-2)18(21)16(10)17/h4-5,9,12,21-22H,6-8H2,1-3H3/t12-/m0/s1
InChI Key	WHFUDAOCYRYAKQ-LBPRGKRZSA-N
Boiling Point	529.3ºC at 760 mmHg
Melting Point	245 °C
Flash Point	273.9ºC
Purity	95%+
Density	1.29g/cm³
Storage	store at <-15℃
Complexity	461
Covalently-Bonded Unit Count	1
Defined Atom Stereocenter Count	1
Exact Mass	327.14705815
Harmonized Tariff Code	Switzerland: 29398000 - USA: 2939800000 - Slovakia: 2939800000 - UK: 2939800000 - China: 2939800000
Heavy Atom Count	24
Hydrogen Bond Acceptor Count	5
Hydrogen Bond Donor Count	2
Isomeric SMILES	CN1CCC2=CC(=C(C3=C2[C@@H]1CC4=C3C(=C(C=C4)OC)O)O)OC
MDL Number	MFCD06809887
Monoisotopic Mass	327.14705815
PhysicalState	Powder
Rotatable Bond Count	2
Topological Polar Surface Area	62.2 Ų

Custom Q&A

What is the product name of corytuberine?

The product name of corytuberine is corytuberine.

What are some synonyms of corytuberine?

Some synonyms of corytuberine include 2,10-Dimethoxy-6aα-aporphine-1,11-diol and (S)-Corytuberine.

What is the CAS number of corytuberine?

The CAS number of corytuberine is 517-56-6.

What is the molecular formula of corytuberine?

The molecular formula of corytuberine is C19H21NO4.

What are some product categories that corytuberine belongs to?

Some product categories that corytuberine belongs to include Aromatics, Chiral Reagents, and Pharmaceuticals.

What is the melting point of corytuberine?

The melting point of corytuberine is 245℃.

What is the boiling point of corytuberine?

The boiling point of corytuberine is 529.3±50.0 °C (Predicted).

What is the density of corytuberine?

The density of corytuberine is 1.290±0.06 g/cm3 (20 ºC 760 Torr).

What is the pka value of corytuberine?

The pka value of corytuberine is 9.20±0.20 (Predicted).

What is the usage of corytuberine?

The usage of corytuberine includes being a semi-synthetic aristolactams-inhibitor of CDK2 enzyme as an antiproliferative agent.

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