Deacetylakuammiline

Catalog Number	ACM1897309
CAS Number	1897-30-9
Structure
Description	Deacetylakuammiline is a monoterpenoid indole alkaloid that has been shown to have anticancer activity. It is structurally related to strictine and apocynin, which are also found in the Apocynaceae family of plants. Deacetylakuammiline has been shown to be effective against leukemia cells, colorectal carcinoma, and colon cancer cells. The anticancer properties of deacetylakuammiline may be due to its ability to reduce blood pressure and inhibit platelet aggregation. Deacetylakuammiline has shown cytotoxic effects on tumor cells by binding and inhibiting the enzyme ATP synthase, which is essential for energy production in the cell. This binding leads to increased reactive oxygen species production, which can cause DNA damage or apoptosis (cell death).
Synonyms	RhazimolErcinaminine
Molecular Weight	352.43 g/mol
Molecular Formula	C21H24N2O3
Canonical SMILES	C/C=C\1/CN2CC[C@@]34C5=CC=CC=C5N=C3[C@@H]2C[C@@H]1C4(CO)C(=O)OC

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