Dihydroergotoxine mesylate

Dihydroergotoxine mesylate

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Catalog Number ACM8067241
CAS Number 8067-24-1
Structure
Synonyms Hydergine
Molecular Weight 423.53
Purity 95%+
PhysicalState Powder
Custom Q&A

What is the chemical formula of Dihydroergotoxine mesylate?

The chemical formula of Dihydroergotoxine mesylate is C20H29N3O5S.

What is the molecular weight of Dihydroergotoxine mesylate?

The molecular weight of Dihydroergotoxine mesylate is 423.53 g/mol.

What is the storage temperature recommended for Dihydroergotoxine mesylate?

Dihydroergotoxine mesylate should be stored at room temperature.

What are the safety statements associated with Dihydroergotoxine mesylate?

The safety statements for Dihydroergotoxine mesylate are 53-36/37/39-45.

What are the uses of Dihydroergotoxine mesylate?

Dihydroergotoxine mesylate is used as a cognition adjuvant and in the treatment of mild to moderate dementia.

What is the brand name of Dihydroergotoxine mesylate?

The brand name of Dihydroergotoxine mesylate include Alkergot, Circanol, Deapril, Gerimal, and Hydergine.

What biological activity does Dihydroergotoxine mesylate exhibit?

Dihydroergotoxine mesylate binds with high affinity to the GABAA receptor Cl- channel and interacts with central dopaminergic, serotonergic and adrenergic (α1) receptors.

How does Dihydroergotoxine mesylate affect prostate cancer cells in vitro?

Dihydroergotoxine mesylate exhibits antiproliferative activity in prostate cancer cells with an IC50 range of 18-38 µM.

What are the pharmacological effects of ergoloid mesylates?

The metabolic effects of ergoloid mesylates may include enhancement of noradrenergic, dopaminergic, and serotoninergic neurotransmission, and reduction of free radicals.

How does Dihydroergotoxine mesylate compare in efficacy to placebo for the treatment of VaD and AD?

Patients with VaD appeared to benefit more than patients with AD in terms of cognition and clinical global ratings with Dihydroergotoxine mesylate, but efficacy compared to placebo was very modest.

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