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Catalog Number | ACM518183-1 |
CAS Number | 518-18-3 |
Description | Evodiamine is a natural compound that induces apoptosis in cells. It has been shown to induce cell death in preadipocytes, 3T3-L1 cells, and cancer cells. Evodiamine binds to the DNA molecule and inhibits the DNA binding activity of transcription factors. This leads to an accumulation of p53 protein, which initiates the apoptotic pathway. Evodiamine has also been shown to synergize with other drugs such as paclitaxel or doxorubicin, both of which are chemotherapeutic agents used for cancer treatment. |
Molecular Weight | 303.36 g/mol |
Molecular Formula | C19H17N3O |
Canonical SMILES | CN1C2C3=C(CCN2C(=O)C4=CC=CC=C41)C5=CC=CC=C5N3 |
Harmonized Tariff Code | Switzerland: 29339910 - USA: 2933999701 - Slovakia: 2933991000 - UK: 2933990000 - China: 2933990090 |
MDL Number | MFCD00016673 |
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