Fasudil hydrochloride

Catalog Number	ACM105628077
CAS Number	105628-07-7
Structure
Synonyms	Eril
IUPAC Name	5-(1,4-Diazepan-1-ylsulfonyl)isoquinoline;hydrochloride
Molecular Weight	327.83
Molecular Formula	C14H18ClN3O2S
Canonical SMILES	C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl
InChI	InChI=1S/C14H17N3O2S.ClH/c18-20(19,17-9-2-6-15-8-10-17)14-4-1-3-12-11-16-7-5-13(12)14;/h1,3-5,7,11,15H,2,6,8-10H2;1H
InChI Key	LFVPBERIVUNMGV-UHFFFAOYSA-N
Purity	98%+
Storage	Store in dry, low temperature, sealed, 2-8 °C.
Complexity	421
Exact Mass	327.0808257
Heavy Atom Count	21
Monoisotopic Mass	327.0808257
Topological Polar Surface Area	70.7Ų

Custom Q&A

What is the chemical name of Fasudil hydrochloride?

The chemical name of Fasudil hydrochloride is 1-(5-ISOQUINOLINESULFONYL)HOMOPIPERAZINE HYDROCHLORIDE.

What are the synonyms for Fasudil hydrochloride?

The synonyms for Fasudil hydrochloride include Fasudil Monohydrochloride, HA-1077, and FASUDEL.

What is the molecular formula of Fasudil hydrochloride?

The molecular formula of Fasudil hydrochloride is C14H18ClN3O2S.

How is Fasudil hydrochloride stored?

Fasudil hydrochloride should be stored in an inert atmosphere, in a freezer, under -20°C.

What is the solubility of Fasudil hydrochloride in water?

Fasudil hydrochloride is soluble in water (>200 mg/mL).

What are the indications and usage of Fasudil hydrochloride?

Fasudil Hydrochloride is used to improve symptoms of ischemic cerebrovascular disease such as cerebral vasospasm following subarachnoid hemorrhage.

What are the mechanisms of action of Fasudil hydrochloride?

Fasudil Hydrochloride is an RHO kinase inhibitor that dilates vessels, reduces tension of endothelial cells, and promotes recovery of neural function.

What are some adverse reactions of Fasudil hydrochloride?

Adverse reactions may include intracranial hemorrhage, gastrointestinal bleeding, pulmonary hemorrhage, and loss of consciousness among others.

What are some warnings and precautions for using Fasudil hydrochloride?

Patients with intracranial hemorrhage, low blood pressure, diabetes mellitus, and liver or kidney dysfunction should exercise caution when using Fasudil hydrochloride.

What is the brand name for Fasudil hydrochloride?

The brand name for Fasudil hydrochloride is Eril.

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