Genisteine

Catalog Number	ACM446957-2
CAS Number	446-95-7
Description	Genisteine is a natural product that is found in plants and soybeans. It has been shown to have cytostatic, antineoplastic, anti-inflammatory, and antioxidant properties. Genisteine has been shown to inhibit the growth of human skin cancer cells by binding to nitrogen atoms of guanine in DNA. The reaction mechanism appears to involve a hydrogen tartrate-mediated oxidation of genisteine followed by a nucleophilic attack on the DNA. X-ray diffraction data show that genisteine forms one or two well defined coordination geometries with the DNA molecule. In addition, structural analysis shows that genisteine binds to the phosphate group of dna polymerase chain reaction (PCR) primers and inhibits PCR activity. This inhibition may be due to steric hindrance or because genisteine competes with primer for binding sites on the template strand. Genisteine also inhibits protein synthesis by inhibiting RNA polymerase II activity in vitro and in vivo
Synonyms	11-Isosparteinel-beta-Isosparteine (Alkaloid)
Molecular Weight	234.38 g/mol
Molecular Formula	C15H26N2
Canonical SMILES	C1CCN2C[C@@H]3C[C@H]([C@H]2C1)CN4[C@@H]3CCCC4
Storage	store at 10℃-25℃
Harmonized Tariff Code	Switzerland: 29224920 - USA: 2922493000 - Slovakia: 2922498000 - UK: 2922498500 - China: 2922490090
MDL Number	MFCD00135841

Custom Q&A

What is the chemical formula of Genisteine?

The chemical formula of Genisteine is C15H26N2.

What is the molecular weight of Genisteine?

The molecular weight of Genisteine is 234.38 g/mol.

At what temperature does Genisteine melt?

Genisteine melts at a temperature of 108-110°C.

What is the specific rotation of Genisteine in absolute ethanol?

The specific rotation of Genisteine in absolute ethanol is -51.6°.

What is the boiling point range of Genisteine?

The boiling point range of Genisteine is 70-85°C at a pressure of 0.1 Torr.

What is the density of Genisteine?

The predicted density of Genisteine is 1.08±0.1 g/cm3.

What is the pKa value of Genisteine?

The pKa value of Genisteine is 10.08±0.20.

What is the main usage of Genisteine Hydrochloride?

Genisteine Hydrochloride is a salt analog of Genisteine that is used as a tyrosine kinase inhibitor in studies on Rous sarcoma virus and human cytomegalovirus.

What role does Genisteine play as a plant metabolite?

Genisteine plays a role as a plant metabolite.

How is Genisteine chemically defined according to ChEBI?

According to ChEBI, Genisteine is a quinolizidine alkaloid that is sparteine in which the hydrogen atom at position 6 is in the beta-configuration.

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