(+)-Glaucine

Catalog Number	ACM475810-1
CAS Number	475-81-0
Description	(+)-Glaucine is a biologically active molecule that is used in the treatment of chronic cough. It has been shown to inhibit the production of inflammatory cytokines and chemokines, such as IL-8 and TNF-α. (+)-Glaucine also inhibits toll-like receptor (TLR) signaling, which is involved in the activation of inflammatory response. (+)-Glaucine binds to 5HT2 receptors on human polymorphonuclear leukocytes and blocks their activation by suppressing NF-κB activity. The drug has been shown to have anti-inflammatory effects on mouse tumor cells and curcuma aromatica cells, where it inhibits DNA intercalation.
Synonyms	1,2,9,10-TetramethoxyaporphineBoldine dimethyletherGlaucine
Molecular Weight	355.43 g/mol
Molecular Formula	C21H25NO4
Canonical SMILES	CN1CCC2=CC(=C(C3=C2[C@@H]1CC4=CC(=C(C=C43)OC)OC)OC)OC
Storage	store at 2℃-8℃
Harmonized Tariff Code	Switzerland: 29339980 - USA: 2933997900 - Slovakia: 2933998090 - UK: 2933998090 - China: 2933990099
MDL Number	MFCD00075953

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