Graveoline

Catalog Number	ACM485610-1
CAS Number	485-61-0
Description	Graveoline is a natural compound that belongs to the group of surfactants. It inhibits acetylcholinesterase, which leads to an accumulation of acetylcholine at the synapses of the central nervous system. Graveoline also has antimicrobial properties and is used in eye drops for the treatment of eye disorders such as dry eye and allergic conjunctivitis. The surfactant can be extracted from plants such as acridone, anthranilic acid and acridone. These compounds inhibit bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase or conjugation with glucuronic acid. Graveoline also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ES
Molecular Weight	279.29 g/mol
Molecular Formula	C17H13NO3
Canonical SMILES	CN1C2=CC=CC=C2C(=O)C=C1C3=CC4=C(C=C3)OCO4
Storage	store at 10℃-25℃, close container well
Harmonized Tariff Code	Switzerland: 29397900 - USA: 2939790000 - Slovakia: 2939799090 - UK: 2939799090 - China: 2939799099
MDL Number	MFCD00236478

Custom Q&A

What is the chemical formula for Graveoline?

The chemical formula for Graveoline is C17H13NO3.

What is the molecular weight of Graveoline?

The molecular weight of Graveoline is 279.29.

At what temperature does Graveoline melt?

Graveoline melts at a temperature of 188 - 189°C.

How should Graveoline be stored?

Graveoline should be stored in a refrigerator.

In what form does Graveoline occur?

Graveoline occurs in solid form.

What color is Graveoline?

Graveoline is white to off-white in color.

In what type of solvents is Graveoline slightly soluble?

Graveoline is slightly soluble in chloroform and methanol.

What is the natural occurrence of Graveoline?

Graveoline is a quinolone alkaloid and occurs in the extract of Haplophyllum dubium.

What physical form does Graveoline take when crystallized from MeOH?

Graveoline forms colorless prisms when crystallized from MeOH.

What is the specific role of Graveoline in skin melanoma cancer cells?

Graveoline is an apoptosis and autophagy inducer in skin melanoma cancer cells.

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