Indirubin

Catalog Number	ACM479414
CAS Number	479-41-4
Structure
Synonyms	Indigopurpurin
Molecular Weight	262.26
InChI	InChI=1S/C16H10N2O2/c19-15-10-6-2-4-8-12(10)17-14(15)13-9-5-1-3-7-11(9)18-16(13)20/h1-8,18,20H
InChI Key	JNLNPCNGMHKCKO-UHFFFAOYSA-N
Melting Point	350 °C
Purity	98%+
Complexity	448
Covalently-Bonded Unit Count	1
Defined Atom Stereocenter Count	0
Exact Mass	262.074227566
Heavy Atom Count	20
Hydrogen Bond Acceptor Count	3
Hydrogen Bond Donor Count	2
Monoisotopic Mass	262.074227566
PhysicalState	Powder
Rotatable Bond Count	1
Topological Polar Surface Area	65.4 Ų

Custom Q&A

What is the chemical formula for Indirubin?

The chemical formula for Indirubin is C16H10N2O2.

What is the melting point of Indirubin?

The melting point of Indirubin is 350°C.

What is the solubility of Indirubin in DMSO?

Indirubin is slightly soluble in DMSO.

What are the main reported pharmacological effects of Indirubin?

The main reported pharmacological effects of Indirubin are anti-inflammatory, antibacterial, detoxification, enhancement of immune function, and anticancer properties.

How is Indirubin traditionally used in Chinese medicine?

Indirubin is the active ingredient in traditional Chinese medicine for treating chronic diseases like chronic myelocytic leukemia.

What is the main pharmacological target of Indirubin and its analogues?

Indirubin and its analogues are potent inhibitors of cyclin-dependent kinases (CDKs).

What is the main clinical use of Indirubin?

Indirubin is mainly used in the clinical treatment of chronic myeloid leukemia.

What is the color and form of Indirubin?

Indirubin is a purple powder with a dark red color.

What is the main inhibitory activity of Indirubin?

Indirubin is an inhibitor of GSK-3β and cyclin-dependent kinases.

What is the reported total effective rate of Indirubin in treating chronic myeloid leukemia?

The reported total effective rate of Indirubin in treating chronic myeloid leukemia is 87.3%.

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