Jervine

Catalog Number	ACM469590
CAS Number	469-59-0
Description	Jervine is a natural drug that has been shown to have synergistic effects with other drugs, such as angiogenic processes and matrix effects. Jervine is an ester hydrochloride derived from the bark of the tree Jervisia japonica. It has been shown to have significant cytotoxicity against human leukemia cells HL-60 in vitro. The mechanism of action of jervine is not yet fully understood, but it may be due to the presence of nitrogen atoms or sesquiterpene lactones.
Synonyms	(3β,23β)-17,23-Epoxy-3-hydroxyveratraman-11-one
Molecular Weight	425.6 g/mol
Molecular Formula	C27H39NO3
Canonical SMILES	C[C@H]1C[C@@H]2[C@H]([C@H]([C@]3(O2)CC[C@H]4[C@@H]5CC=C6C[C@H](CC[C@@]6([C@H]5C(=O)C4=C3C)C)O)C)NC1
Storage	store at <-15℃, close container well
Harmonized Tariff Code	Switzerland: 29397900 - USA: 2939790000 - Slovakia: 2939799090 - UK: 2939490090 - China: 2939799099
MDL Number	MFCD01684066

Custom Q&A

What is the chemical formula of JERVINE?

The chemical formula of JERVINE is C27H39NO3.

What is the melting point of JERVINE?

The melting point of JERVINE is 242-244°C.

What is the alpha value of JERVINE in ethanol?

The alpha value of JERVINE in ethanol is -150°.

How is JERVINE stored?

JERVINE is stored at -20°C.

What is the solubility of JERVINE in methanol?

The solubility of JERVINE in methanol is greater than 2 mg/mL.

What are the hazard codes associated with JERVINE?

The hazard codes associated with JERVINE are Xn.

What are the usage and synthesis of JERVINE?

JERVINE was first obtained from Veratrum grandiflorum and has antibacterial properties. It demonstrates teratogenic properties and induces holoprosencephaly.

What are the crystal properties of JERVINE?

JERVINE is a white crystalline solid.

What is the boiling point of JERVINE?

The boiling point of JERVINE is estimated to be 541.31°C.

What is the toxicity level of JERVINE in mice?

The LD50 of JERVINE in mice is 9.3 mg/kg when administered intravenously and 29 mg/kg when administered subcutaneously.

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