Ligustrazine

Catalog Number	ACM1124114-1
CAS Number	1124-11-4
Structure
Synonyms	Pyrazine, tetramethyl-
IUPAC Name	2,3,5,6-Tetramethylpyrazine
Molecular Weight	136.19
Molecular Formula	C8H12N2
Canonical SMILES	CC1=C(N=C(C(=N1)C)C)C
InChI	InChI=1S/C8H12N2/c1-5-6(2)10-8(4)7(3)9-5/h1-4H3
InChI Key	FINHMKGKINIASC-UHFFFAOYSA-N
Purity	98%+ (HPLC)
Storage	Store in dry, low temperature, sealed, 2-8 °C.
Complexity	87.8
Exact Mass	136.100048391
Heavy Atom Count	10
Monoisotopic Mass	136.100048391
Topological Polar Surface Area	25.8Ų

Custom Q&A

What is another name for Tetramethylpyrazine according to the reference?

Ligustrazine

What is the molecular formula of Tetramethylpyrazine?

C8H12N2

What is the boiling point of Tetramethylpyrazine?

190°C

What are some uses of Tetramethylpyrazine?

It can be used for the treatment of cardiovascular problems, diabetes, and as a flavoring agent in various products.

How is Tetramethylpyrazine prepared?

It is generated by condensing butanedione monoxime and ethyl nitrite, then reducing and cyclizing the product.

In what type of products is Tetramethylpyrazine naturally found?

It is reported to be found in cocoa products, coffee, meats, beans, and various other foods.

What are some safety precautions for Tetramethylpyrazine?

It is stable but incompatible with strong acids and oxidizing agents.

How does Tetramethylpyrazine affect the blood vessels according to the reference?

It induces vasodilation in rat tissue and reduces blood pressure.

What are the characteristics of the odor of Tetramethylpyrazine?

It is described as nutty, musty, chocolate, coffee, cocoa, and brown when diluted.

What are some of the reported pharmacological effects of Tetramethylpyrazine in the reference?

It can inhibit phosphodiesterase activity, inhibit platelet aggregation, and improve microcirculation.

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