(+)-Magnoflorine iodide

Catalog Number	ACM4277434-2
CAS Number	4277-43-4
Description	(+)-Magnoflorine iodide is a compound that inhibits matrix metalloproteinase (MMP) activity. It has been shown to inhibit MMP-2 and MMP-9 at different concentrations, with the IC50 values being 0.5 to 1 μM and 3 to 5 μM, respectively. These results suggest that (+)-Magnoflorine iodide may have therapeutic potential for the treatment of diseases associated with MMPs. The chemical reactions of (+)-Magnoflorine iodide are related to its acidic nature. It undergoes a number of reactions including hydrolysis, oxidation, reduction, and chlorination. Chromatographic analysis has revealed that (+)-Magnoflorine iodide is composed of protopine, cryptopine, dictamnine, and chloride ions. Chelerythrine chloride is a metabolite of this compound which can be detected in urine after oral administration.
Synonyms	Thalictrine iodide
Molecular Weight	469.31 g/mol
Molecular Formula	C20H24NO4·I
Canonical SMILES	C[N+]1(CCC2=CC(=C(C3=C2[C@@H]1CC4=C3C(=C(C=C4)OC)O)O)OC)C.[I-]
Storage	store at <-15℃, close container well
Harmonized Tariff Code	Switzerland: 29397900 - USA: 2939790000 - Slovakia: 2939799090 - UK: 2939490090 - China: 2939799099
MDL Number	MFCD03427294

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