9-Methoxycamptothecin

Catalog Number	ACM39026921
CAS Number	39026-92-1
Description	9-Methoxycamptothecin (MCPT), isolated from Camptotheca acuminata, has antitumor activities through topoisomerase inhibition. 9-Methoxycamptothecin (MCPT) induces strong G2/M arrest and apoptosis in cancer.
Synonyms	(4S)-10-Methoxy-4α-ethyl-4β-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Molecular Weight	378.4
Molecular Formula	C21H18N2O5
Canonical SMILES	CC[C@@]1(C2=C(COC1=O)C(N3C(C4=NC5=CC=CC(OC)=C5C=C4C3)=C2)=O)O
InChI	InChI=1S/C21H18N2O5/c1-3-21(26)14-8-16-18-11(7-12-15(22-18)5-4-6-17(12)27-2)9-23(16)19(24)13(14)10-28-20(21)25/h4-8,26H,3,9-10H2,1-2H3/t21-/m0/s1
InChI Key	XVMZDZFTCKLZTF-NRFANRHFSA-N
Melting Point	223-225 °C
Purity	95%+
Appearance	Solid
Storage	4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light).
Complexity	790
Covalently-Bonded Unit Count	1
Defined Atom Stereocenter Count	1
Exact Mass	378.12157168
Heavy Atom Count	28
Hydrogen Bond Acceptor Count	6
Hydrogen Bond Donor Count	1
Isomeric SMILES	CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=C(C=CC=C5OC)N=C4C3=C2)O
Monoisotopic Mass	378.12157168
PhysicalState	Powder
Rotatable Bond Count	2
Topological Polar Surface Area	89 Ų

Custom Q&A

What is the chemical formula of 9-methoxycamptothecin?

The chemical formula of 9-methoxycamptothecin is C21H18N2O5.

What is the molecular weight of 9-methoxycamptothecin?

The molecular weight of 9-methoxycamptothecin is 378.38.

What is the melting point of 9-methoxycamptothecin?

The melting point of 9-methoxycamptothecin is 254-255℃.

In what solvents is 9-methoxycamptothecin soluble?

9-methoxycamptothecin is soluble in Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.

How is the structure of 9-methoxycamptothecin established?

The structure of 9-methoxycamptothecin is established by spectroscopic methods.

What is the use of 9-methoxycamptothecin?

9-methoxycamptothecin is used in the treatment of cancers and hyperproliferative diseases.

What is the storage temperature recommended for 9-methoxycamptothecin?

9-methoxycamptothecin should be stored at 4°C and protected from light.

What is the boiling point of 9-methoxycamptothecin?

The predicted boiling point of 9-methoxycamptothecin is 773.1±60.0 °C.

What is the pka value of 9-methoxycamptothecin?

The pka value of 9-methoxycamptothecin is 11.21±0.20.

What are some synonyms for 9-methoxycamptothecin?

Some synonyms for 9-methoxycamptothecin include 10-Methoxycamptothecin, 10-Methoxycamptothecin, and 10-Methoxycamptothecin.

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