Methyl reserpate

Catalog Number	ACM2901668-1
CAS Number	2901-66-8
Structure
Synonyms	Reserpic acid methyl ester
Molecular Weight	414.5
InChI	InChI=1S/C23H30N2O5/c1-28-13-4-5-14-15-6-7-25-11-12-8-19(26)22(29-2)20(23(27)30-3)16(12)10-18(25)21(15)24-17(14)9-13/h4-5,9,12,16,18-20,22,24,26H,6-8,10-11H2,1-3H3/t12-,16+,18-,19-,20+,22+/m1/s1
InChI Key	MDJQWFFIUHUJSB-UQVJXISSSA-N
Melting Point	244.5 °C
Purity	95%+
Complexity	647
Covalently-Bonded Unit Count	1
Defined Atom Stereocenter Count	6
Exact Mass	414.21547206
Heavy Atom Count	30
Hydrogen Bond Acceptor Count	6
Hydrogen Bond Donor Count	2
Isomeric SMILES	CO[C@H]1[C@@H](C[C@@H]2CN3CCC4=C([C@H]3C[C@@H]2[C@@H]1C(=O)OC)NC5=C4C=CC(=C5)OC)O
Monoisotopic Mass	414.21547206
PhysicalState	Powder
Rotatable Bond Count	4
Topological Polar Surface Area	84 Ų

Custom Q&A

What is the chemical name of reserpine?

The chemical name of reserpine is Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-(3,4,5-trimethoxybenzoyl)oxy-, methyl ester, (3.beta.,16.beta.,17.alpha.,18.beta.,20.alpha.).

What are some synonyms for reserpine?

Some synonyms for reserpine are SERPASIL, and RESERPINE (RG).

What is the Melting point of reserpine?

The melting point of reserpine is approximately 265°C.

What is the primary indication for reserpine?

Reserpine is primarily indicated for the treatment of hypertension and schizophrenia.

How does reserpine work in the body to reduce hypertension?

Reserpine depletes catecholamines from peripheral sympathetic nerve endings, which results in lowering blood pressure.

What are some common adverse reactions to reserpine?

Some common adverse reactions to reserpine include dizziness, dry mouth, headache, muscle pain, anxiety, and weight gain.

What precautions should be taken by patients before using reserpine?

Patients with a history of allergic reactions, depression, stomach ulcers, or kidney disease should consult their doctor before using reserpine. Breastfeeding is not recommended while taking this drug.

What safety codes and statements are associated with reserpine?

Reserpine is associated with Hazard Codes Xn, Xi and varies Risk and Safety Statements.

How does reserpine weaken the intracellular uptake of biogenic amines?

Reserpine weakens the intracellular uptake of biogenic amines by inhibiting the ATP/Mg2+ pump responsible for storing them in vesicles.

What is the historical significance of reserpine in the treatment of hypertension?

Reserpine was first isolated in 1952 and won an important status in treating hypertension and neurological disorders due to its remarkable physiological attributes.

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