Noscapine hydrochloride

Catalog Number	ACM912607
CAS Number	912-60-7
Structure
Synonyms	1-alpha-Narcotinehydrochloride
IUPAC Name	(3S)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-2-benzofuran-1-one hydrochloride
Molecular Weight	449.9
Molecular Formula	C22H23NO7.HCl
Canonical SMILES	CN1CCC2=CC3=C(C(=C2C1C4C5=C(C(=C(C=C5)OC)OC)C(=O)O4)OC)OCO3.O.Cl
InChI	InChI=1S/C22H23NO7.ClH/c1-23-8-7-11-9-14-20(29-10-28-14)21(27-4)15(11)17(23)18-12-5-6-13(25-2)19(26-3)16(12)22(24)30-18;/h5-6,9,17-18H,7-8,10H2,1-4H3;1H/t17-,18+;/m1./s1
InChI Key	MFLVZFXCSKVCSH-URBRKQAFSA-N
Boiling Point	565.3ºC at 760mmHg
Melting Point	221-223 °C
Flash Point	295.7ºC
Purity	98%+
Density	1.332g/cm³
Complexity	647
Covalently-Bonded Unit Count	2
Defined Atom Stereocenter Count	2
EC Number	213-014-9
Exact Mass	449.1241298
Hazard Statements	Xi:Irritant;
Heavy Atom Count	31
Hydrogen Bond Acceptor Count	8
Hydrogen Bond Donor Count	1
Isomeric SMILES	CN1CCC2=CC3=C(C(=C2[C@@H]1[C@@H]4C5=C(C(=C(C=C5)OC)OC)C(=O)O4)OC)OCO3.Cl
Monoisotopic Mass	449.1241298
Packing Group	III
PhysicalState	Solid
Rotatable Bond Count	4
Topological Polar Surface Area	75.7 Ų

Custom Q&A

What is the chemical formula of Noscapine hydrochloride?

The chemical formula of Noscapine hydrochloride is C22H24ClNO7.

What is the melting point of Noscapine hydrochloride?

The melting point of Noscapine hydrochloride is 221-223°C.

In what form is Noscapine hydrochloride stored?

Noscapine hydrochloride is stored in a temperature range of 2-8°C.

What is the solubility of Noscapine hydrochloride?

Noscapine hydrochloride is freely soluble in water and in ethanol (96 per cent).

What are the hazard codes associated with Noscapine hydrochloride?

The hazard codes associated with Noscapine hydrochloride are Xn and Xi.

What is the primary usage of Noscapine hydrochloride?

Noscapine hydrochloride is used as an anti-tussive agent.

What type of inhibitor is Noscapine hydrochloride?

Noscapine hydrochloride is a bradykinin B and tubulin inhibitor.

What is the safety profile of Noscapine hydrochloride?

Noscapine hydrochloride is moderately toxic by ingestion and subcutaneous routes.

What are the safety statements associated with Noscapine hydrochloride?

The safety statements associated with Noscapine hydrochloride are 36.

What are the biological activities of Noscapine hydrochloride?

Noscapine hydrochloride binds to tubulin, arrests cells in mitosis, induces apoptosis, and acts as an antagonist at bradykinin receptors. It is also an anti-viral agent.

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