Oxymatrine

Catalog Number	ACM16837528-2
CAS Number	16837-52-8
Structure
Description	This compound is an alkaloid found in the roots of leguminous plants of Sophora genus. It has a range of pharmacological effects and acts as anti-inflammatory, anti-fibrotic and anti-cancer agent. Oxymatrine has anti-proliferative and anti-angiogenic properties since it inhibits the growth of pancreatic cancer cells and the expression of angiogenesis-associated factors VEGF and NF-κB. It has been also reported that the compound attenuates memory impairment and amyloid-induced neurotoxicity in neuronal cells.
Synonyms	Ammothamnine
Molecular Weight	264.36 g/mol
Molecular Formula	C15H24N2O2
Canonical SMILES	C1C[C@@H]2[C@H]3CCC[N+]4([C@H]3[C@@H](CCC4)CN2C(=O)C1)[O-]
InChI	InChI=1S/C15H24N2O2/c18-14-7-1-6-13-12-5-3-9-17(19)8-2-4-11(15(12)17)10-16(13)14/h11-13,15H,1-10H2/t11-,12+,13+,15-,17/m0/s1
InChI Key	XVPBINOPNYFXID-LHDUFFHYSA-N
Melting Point	208 °C
Purity	98%+
Appearance	Solid
Storage	store at 2℃-8℃, keep dry
Complexity	400
Covalently-Bonded Unit Count	1
Defined Atom Stereocenter Count	4
Exact Mass	264.183778013
Harmonized Tariff Code	Switzerland: 29398000 - USA: 2939800000 - Slovakia: 2939800000 - UK: 2939800000 - China: 2939809000
Heavy Atom Count	19
Hydrogen Bond Acceptor Count	2
Hydrogen Bond Donor Count	0
Isomeric SMILES	C1C[C@@H]2[C@H]3CCC[N+]4([C@H]3[C@@H](CCC4)CN2C(=O)C1)[O-]
MDL Number	MFCD00210339
Monoisotopic Mass	264.183778013
PhysicalState	Powder
Rotatable Bond Count	0
Topological Polar Surface Area	38.4 Ų

Custom Q&A

What is the chemical formula for Ammothamnine?

The chemical formula for Ammothamnine is C15H24N2O2.

What is the molecular weight of Ammothamnine?

The molecular weight of Ammothamnine is 264.36.

What is the melting point of Ammothamnine?

The melting point of Ammothamnine is 208℃.

What is the solubility of Ammothamnine in methanol?

Ammothamnine is soluble in methanol at 10mg/mL.

What are the safety hazard codes associated with Ammothamnine?

The hazard code for Ammothamnine is Xn.

What is the usage and synthesis of Ammothamnine?

Ammothamnine is an alkaloid from Sophora angustifolia var. flavescens and it is formed by the action of hydrogen peroxide on Matrine.

What are the properties of Oxymatrine?

Oxymatrine is a natural alkaloid with antiviral properties, anti-tumor agent, and hepatoprotectant.

How does Oxymatrine prevent fibrosis in certain organs?

Oxymatrine prevents fibrosis by interfering with TGF-β signaling.

What are the safety statements associated with Ammothamnine?

The safety statements for Ammothamnine are 24/25.

What are the uses of Oxymatrine?

Oxymatrine is used as an anti-tumor agent triggering apoptosis in human leukemia cells and as an antifungal and hepatoprotectant.

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