Picropodophyllin

Catalog Number	ACM477474-2
CAS Number	477-47-4
Description	Picropodophyllin is a natural product that has been shown to inhibit the growth of human cancer cells in vitro. It has been found to activate apoptosis, which may be due to its ability to induce pro-apoptotic protein expression and inhibition of the protein synthesis pathway. Picropodophyllin is also able to bind to receptors, such as those for 5HT (serotonin) and dopamine. This binding leads to an increase in cAMP levels, which may be responsible for the observed cell death.
Synonyms	(5R,5aS,8aR,9R)-5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one
Molecular Weight	414.41 g/mol
Molecular Formula	C22H22O8
Canonical SMILES	COC1=CC(=CC(=C1OC)OC)[C@H]2[C@H]3[C@H](COC3=O)[C@H](C4=CC5=C(C=C24)OCO5)O
Storage	store at 2℃-8℃
Harmonized Tariff Code	Switzerland: 29322000 - USA: 2932205050 - Slovakia: 2932209090 - UK: 2932209000 - China: 2932209090
MDL Number	MFCD01742647

Custom Q&A

What is the chemical formula of Picropodophyllin?

The chemical formula of Picropodophyllin is C22H22O8.

What is the melting point of Picropodophyllin?

The melting point of Picropodophyllin is 225-227°C.

What is the primary usage of Picropodophyllin?

The primary usage of Picropodophyllin is as an insulin-like growth factor 1 receptor inhibitor.

How is Picropodophyllin stored?

Picropodophyllin is stored sealed in dry at 2-8°C.

What is the solubility of Picropodophyllin?

Picropodophyllin is soluble in water.

What is the safety information associated with Picropodophyllin?

The hazard codes for Picropodophyllin are Xi and T, with specific risk and safety statements.

What is the biological activity of Picropodophyllin?

Picropodophyllin is an orally active insulin-like growth factor 1 receptor inhibitor that exhibits antiproliferative effects and anticancer activity in vivo.

How does Picropodophyllin affect cell cycle?

Picropodophyllin induces G2-M cell cycle arrest in cells.

What are the potential applications of Picropodophyllin?

Picropodophyllin has potential applications as an antineoplastic agent and in inhibiting angiogenesis.

What is the stability of Picropodophyllin?

Picropodophyllin is stable for 1 year from the date of purchase as supplied, and solutions in DMSO may be stored at -20°C for up to 1 month.

※ Please kindly note that our products are for research use only.