Rauwolscine hydrochloride

Catalog Number	ACM6211321-1
CAS Number	6211-32-1
Description	Rauwolscine hydrochloride is a potent antagonist of the 5-HT2 receptor. It has been shown to inhibit the replication of HIV in tissue culture and to block the binding of 5-HT to its receptor. Rauwolscine hydrochloride also blocks 5-HT7 receptors, which are found in gland cells and have been implicated in infectious diseases. Rauwolscine hydrochloride has shown to inhibit mitochondrial activity when injected into the femoral vein of rats. This inhibition was shown to be due to a direct interaction with mitochondrial inhibitors such as cytochrome C oxidase, succinate dehydrogenase, and adenylate kinase. The drug has been shown to bind selectively with high affinity to rat brain 5-HT2 receptors in the caudate putamen region of the brain and also inhibits lacrimal gland secretion. Rauwolscine hydrochloride has also been tested on skin models for its potential as an
Molecular Weight	390.9 g/mol
Molecular Formula	C21H26N2O3·HCl
Canonical SMILES	COC(=O)[C@@H]1[C@H](CC[C@H]2[C@@H]1C[C@H]3C4=C(CCN3C2)C5=CC=CC=C5N4)O.Cl
Storage	store at 10℃-25℃
Harmonized Tariff Code	Switzerland: 29397900 - USA: 2939790000 - Slovakia: 2939799090 - UK: 2939799090 - China: 2939799099
MDL Number	MFCD06668052

Custom Q&A

What is the chemical name of Rauwolscine hydrochloride?

α-Yohimbine hydrochloride, 17α-Hydroxy-20α-yohimban-16 β-carboxylic acid methyl ester hydrochloride

What is the molecular formula of Rauwolscine hydrochloride?

C21H27ClN2O3

What is the melting point of Rauwolscine hydrochloride?

270-280°C

What is the color of Rauwolscine hydrochloride?

White

Is Rauwolscine hydrochloride sensitive to light?

Yes, it is light sensitive

What are the risk statements associated with Rauwolscine hydrochloride?

Risk Statements 23/24/25

What is the hazard class of Rauwolscine hydrochloride?

HazardClass 6.1

What are the uses of Rauwolscine hydrochloride?

Rauwolscine acts as a selective and reversible α2-adrenergic receptor antagonist and as a serotonin 5-HT2B receptor antagonist

What are the biological activities of Rauwolscine hydrochloride?

It is a standard α2-adrenergic antagonist and a partial agonist at 5-HT1A receptors

Who showed that Rauwolscine hydrochloride is a cardiovascular depressant with hypotensive activity?

Chakravarti

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