(-)-Stylopine

Catalog Number	ACM84399-1
CAS Number	84-39-9
Description	(-)-Stylopine is a natural product derived from plants of the family Apocynaceae. It inhibits acetylcholinesterase by binding to the enzyme's active site and thus prevents the breakdown of acetylcholine, which leads to an increase in acetylcholine concentrations and subsequent activation of nicotinic receptors. This compound has been shown to be effective against inflammatory diseases such as ulcerative colitis, Crohn's disease, and arthritis. (-)-Stylopine also has anti-cancer activity, inhibiting tumor growth in cell culture by blocking the formation of new blood vessels that supply nutrients to tumors. It may also have anti-inflammatory effects mediated through toll-like receptor 4 (TLR4).
Synonyms	(-)-Tetrahydrocoptisine
Molecular Weight	323.34 g/mol
Molecular Formula	C19H17NO4
Canonical SMILES	C1CN2CC3=C(C[C@H]2C4=CC5=C(C=C41)OCO5)C=CC6=C3OCO6
MDL Number	MFCD00075989

Custom Q&A

What is the product name of the compound discussed in the reference?

The product name is (-)-STYLOPINE.

What are some synonyms of (-)-STYLOPINE?

Some synonyms include 6,7,12b,13-Tetrahydro-4H-[1,3]dioxolo[4',5':7,8]isoquinolino[3,2-a][1,3]dioxolo[4,5-g]isoquinoline, and (RS)-Stylopine.

What is the chemical formula (MF) of (-)-STYLOPINE?

The chemical formula is C19H17NO4.

What is the predicted melting point of (-)-STYLOPINE?

The predicted melting point is 221-222℃.

What is the predicted boiling point of (-)-STYLOPINE?

The predicted boiling point is 466.6±34.0 °C.

What is the storage temperature recommended for (-)-STYLOPINE?

It is recommended to store (-)-STYLOPINE in an inert atmosphere at room temperature.

What are some solubility properties of (-)-STYLOPINE?

It is soluble in DMF and chloroform at different concentrations.

From which plant is dl-Stylopine isolated?

dl-Stylopine is isolated from the whole plant of Argemone mexicana.

What is the importance of (S)-Stylopine in the biosynthesis of benzophenanthridine alkaloids?

(S)-Stylopine is an important intermediate in the biosynthesis of benzophenanthridine alkaloids, such as Sanguinarine.

What is the predicted pka value of (-)-STYLOPINE?

The predicted pka value is 6.53±0.20.

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