Synephrine

Catalog Number	ACM94075
CAS Number	94-07-5
Structure
Synonyms	4-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol
IUPAC Name	4-[1-Hydroxy-2-(methylamino)ethyl]phenol
Molecular Weight	167.21
Molecular Formula	C9H13NO2
Canonical SMILES	CNCC(C1=CC=C(C=C1)O)O
InChI	InChI=1S/C9H13NO2/c1-10-6-9(12)7-2-4-8(11)5-3-7/h2-5,9-12H,6H2,1H3
InChI Key	YRCWQPVGYLYSOX-UHFFFAOYSA-N
Boiling Point	295.79 °C
Melting Point	187 °C(lit.)
Flash Point	163.4 °C
Purity	98%
Density	1.1222 g/cm³
Appearance	Solid
Storage	2-8 °C
Complexity	122
Covalently-Bonded Unit Count	1
Defined Atom Stereocenter Count	0
Exact Mass	167.094628657
Heavy Atom Count	12
Hydrogen Bond Acceptor Count	3
Hydrogen Bond Donor Count	3
Monoisotopic Mass	167.094628657
PhysicalState	Solid
Rotatable Bond Count	3
Topological Polar Surface Area	52.5 Ų

Custom Q&A

What is the chemical name of Synephrine?

The chemical name of Synephrine is p-synephrine.

From which plant is Synephrine mainly extracted?

Synephrine is mainly extracted from the orange, tangerine peel, green husk, and rutaceae plants.

What are some synonyms for Synephrine?

Some synonyms for Synephrine include oxedrine, SYNEPHERINE, and 4-hydroxy-alpha-(methylaminomethyl)benzyl alcohol.

What is the most famous application of Synephrine?

The most famous application of Synephrine is for the treatment of obesity.

What is the mode of action of Synephrine as a weight-loss stimulant?

Synephrine's mechanism of action as a weight-loss stimulant is attributed to the lipolytic effects that occur with the activation of beta3-adrenergic receptors and consequent thermogenesis.

What are some risks associated with the consumption of Synephrine?

Risks associated with the consumption of Synephrine include potential cardiovascular toxicity, reduced locomotor activity, ischemic colitis, and seizures.

How does Synephrine act on adrenergic receptors?

Both m- and p-Synephrine activate several types of adrenergic receptors.

In which countries is the use of Synephrine limited?

Synephrine is limited to use in the United States, Canada, and other countries due to potential side effects of cardiovascular disease.

What is the daily limit of Synephrine established by Health Canada in natural products?

Health Canada established a daily limit of 30 mg as the maximum allowable dose for Synephrine in natural products.

What is a significant increase in systolic pressure associated with Synephrine?

Synephrine may cause a significant increase in systolic pressure as well as promote an increase in total peripheral resistance during 30-60 min in healthy volunteers.

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