Veratridine

Catalog Number	ACM71625
CAS Number	71-62-5
Synonyms	3-Veratroylveracevine
IUPAC Name	[(1R,2S,6S,9S,10R,11S,12S,14R,15S,18S,19S,22S,23S,25R)-1,10,11,12,14,23-Hexahydroxy-6,10,19-trimethyl-24-oxa-4-azaheptacyclo[12.12.0.02,11.04,9.015,25.018,23.019,25]hexacosan-22-yl] 3,4-dimethoxybenzoate
Molecular Weight	673.8
Molecular Formula	C36H51NO11
Canonical SMILES	CC1CCC2C(C3(C(CC4(C5CCC6C7(C5(CC4(C3CN2C1)O)OC6(C(CC7)OC(=O)C8=CC(=C(C=C8)OC)OC)O)C)O)O)O)(C)O
InChI	InChI=1S/C36H51NO11/c1-19-6-11-26-31(3,40)35(43)25(17-37(26)16-19)33(42)18-34-24(32(33,41)15-27(35)38)10-9-23-30(34,2)13-12-28(36(23,44)48-34)47-29(39)20-7-8-21(45-4)22(14-20)46-5/h7-8,14,19,23-28,38,40-44H,6,9-13,15-18H2,1-5H3/t19-,23-,24-,25-,26-,27-,28-,30-,31+,32+,33+,34+,35-,36-/m0/s1
InChI Key	FVECELJHCSPHKY-YFUMOZOISA-N
Melting Point	180 °C
Purity	98%+(HPLC)
Appearance	Light yellow powder
Storage	Store at 4 °C, sealed, away from light (valid for 2 years under this condition).
Complexity	1340
Exact Mass	673.34621144
Heavy Atom Count	48
Isomeric SMILES	C[C@H]1CC[C@H]2[C@@]([C@]3([C@H](C[C@]4([C@@H]5CC[C@H]6[C@]7([C@]5(C[C@]4([C@@H]3CN2C1)O)O[C@@]6([C@H](CC7)OC(=O)C8=CC(=C(C=C8)OC)OC)O)C)O)O)O)(C)O
Monoisotopic Mass	673.34621144
Topological Polar Surface Area	179Ų

Custom Q&A

What is the chemical formula of Veratridine?

The chemical formula of Veratridine is C36H51NO11.

What is the melting point of Veratridine?

The melting point of Veratridine is 180℃.

How is Veratridine stored?

Veratridine is stored at -20°C.

What is the solubility of Veratridine in ethanol?

Veratridine is soluble in ethanol with a concentration of 50 mg/mL.

How long can Veratridine solutions be stored in DMSO or ethanol?

Veratridine solutions can be stored in DMSO or ethanol at -20°C for up to 2 months.

What are the hazard codes associated with Veratridine?

The hazard codes associated with Veratridine are T+.

What is the toxicity of Veratridine in mice?

The LD50 of Veratridine in mice is 1.35 mg/kg i.p. and 0.42 mg/kg i.v.

What effect does Veratridine have on Na+ channels?

Veratridine causes Na+ channels to stay open during a sustained membrane depolarization by abolishing inactivation.

How does Veratridine increase intracellular calcium content?

Veratridine opens voltage-activated calcium channels, thus increasing intracellular calcium content and inducing neurotransmitter release.

What is the role of Veratridine in neurotoxicity?

Veratridine is an alkaloid neurotoxin that depolarizes excitable tissue and is used to increase membrane sodium permeability.

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