Vasopressin

Vasopressin, also known as antidiuretic hormone (ADH), is a cyclic nonapeptide hormone that plays a crucial role in regulating water balance in the body. It is produced by the hypothalamus and released by the posterior pituitary gland in response to changes in blood osmolality. Vasopressin acts on the kidneys to increase water reabsorption, thereby reducing urine output and helping to maintain proper hydration levels in the body.

Alfa Chemistry provides high-quality vasopressin and related product customization services.

structural chemical formula of vasopressin molecular

Product Detail

Product Name	Vasopressin
CAS No.	11000-17-2
Catalog	ALKS11000172
Purity	99.83%
Appearance	White to off-white solid
Molecular Weight	1084.23
Molecular Formula	C46H65N15O12S2
Sequence	Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6)
Structure Classification	Cyclopeptides
Storage	Sealed storage, away from moisture

Applications of Vasopressin

Clinical Uses in Medicine

Vasopressin has various clinical applications in medicine, particularly in the management of conditions such as diabetes insipidus, septic shock, and bleeding disorders. In patients with diabetes insipidus, which is characterized by excessive thirst and urination due to insufficient vasopressin production, exogenous vasopressin administration can help restore water balance and alleviate symptoms.

In cases of septic shock, vasopressin is used as a vasoconstrictor agent to increase blood pressure and improve perfusion to vital organs. By constricting blood vessels and reducing blood flow to peripheral tissues, vasopressin helps maintain adequate blood supply to essential organs during times of hemodynamic instability.

Research and Development

Beyond its clinical applications, vasopressin serves as a valuable tool in research and drug development. Its unique structure and biological activity make it a promising candidate for the design of novel peptide-based therapeutics. Researchers are exploring the potential of vasopressin analogs and derivatives in various areas such as drug delivery, cancer therapy, and metabolic disorders.

Moreover, the study of vasopressin and other cyclopeptides provides insights into the structure-activity relationships of cyclic peptides, paving the way for the development of new drug candidates with improved pharmacokinetic properties and target selectivity.

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