Destruxin B, a cyclodepsipeptide isolated from the entomopathogenic fungus Metarhizium anisopliae, exhibits both insecticidal and anticancer properties. In human non-small cell lung cancer cells, destruxin B induces apoptosis through a mitochondrial pathway that is dependent on the Bcl-2 family. This compound significantly activates caspase-3 and reduces tumor cell proliferation, leading to caspase-mediated apoptosis. These effects have been observed in both in vitro and in vivo studies.
Alfa Chemistry provides high-quality destruxin B and related product customization services.
| Product Name | Destruxin B |
| CAS No. | 2503-26-6 |
| Catalog | ALKS2503266 |
| Purity | ≥ 99% |
| Appearance | White to off-white solid |
| Structure Classification | Cyclopeptides |
| Storage | Sealed storage, away from moisture Powder: : -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month |
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