Berberrubine

Catalog Number	ACM17388191-1
CAS Number	17388-19-1
Structure
Description	Berberrubine is a natural product that has been shown to be active against infectious diseases. Berberrubine is also an inhibitor of the enzyme mitochondrial DNA polymerase beta and may have potential for treating myeloma cell lines. Berberrubine inhibits the expression of enzymes in the pentose phosphate pathway, which is important for energy metabolism in cells. It also has significant up-regulation of genes involved in drug interactions and opportunistic fungal infections such as Aspergillus niger, Candida albicans, and Cryptococcus neoformans. The effect of berberrubine on glycolysis was evaluated by measuring its hypoglycemic effect in diabetic mice. This effect was mediated through a matrix effect and dna intercalation into the cell membrane. Berberrubine also inhibits protein synthesis by binding to ribosomes at or near the peptidyl transferase center, blocking mRNA translocation onto the ribosome surface, inhibiting protein synthesis and leading
Molecular Weight	322.33 g/mol
Molecular Formula	C19H16NO4
Canonical SMILES	COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC5=C(C=C4CC3)OCO5)O
MDL Number	MFCD00151631

Custom Q&A

What is the chemical formula for berberrubine?

The chemical formula for berberrubine is C19H16ClNO4.

What are some synonyms for berberrubine?

Some synonyms for berberrubine include 9-Berberoline chloride, Chileninone, and Nerberrubine.

What is the melting point of berberrubine?

The melting point of berberrubine is 245℃.

How should berberrubine be stored?

Berberrubine should be stored in a hygroscopic, -20°C Freezer, under an inert atmosphere.

In what form does berberrubine exist?

Berberrubine exists in a solid form.

What are some of the chemical properties of berberrubine?

The solubility of berberrubine includes DMSO (Slightly) and Methanol (Slightly).

What is the usage of berberrubine?

Berberrubine Chloride is used as a novel alkaloid with novel nitric-oxide donating activity, as an antitumor agent, and as an antimicrobial agent.

What is the stability of berberrubine?

Berberrubine is hygroscopic in nature.

How is berberrubine classified according to ChEBI?

Berberrubine is classified as an alkaloid.

What are some of the product categories that berberrubine falls under?

Berberrubine falls under product categories such as chemical reagent, pharmaceutical intermediate, phytochemical, reference standards from Chinese medicinal herbs (TCM), and standardized herbal extract.

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