Calycanthine

Catalog Number	ACM595051-1
CAS Number	595-05-1
Description	Calycanthine is a nitrogenous organic compound that has been shown to be an effective treatment for prostate cancer cells. It was found to inhibit the growth of prostate cancer cells and induce apoptosis in a dose-dependent manner. Calycanthine also inhibits the synthesis of quinolizidine alkaloids, which are found in plants such as palicourea and some members of the Solanaceae family. In addition, calycanthine has been shown to have anti-inflammatory effects in chronic bronchitis patients, leading to a reduction in the amount of mucus produced and a decrease in inflammation. The mechanism by which calycanthine exerts its anti-inflammatory effect is not completely understood but may be due to its ability to form hydrogen bonds with proteins and other molecules in the cell membrane.
Synonyms	(4bS)-5,6,11,12-Tetrahydro-13,18-dimethyl-5β,10bβ:11β,4bβ-bis(iminoethano)dibenzo[c,h][2,6]naphthyridine
Molecular Weight	346.47 g/mol
Molecular Formula	C22H26N4
Canonical SMILES	CN1CC[C@@]23[C@@H]4Nc5ccccc5[C@]2(CCN4C)[C@@H]1Nc6ccccc36
InChI	InChI=1S/C22H26N4/c1-25-13-11-22-16-8-4-5-9-17(16)23-19(25)21(22)12-14-26(2)20(22)24-18-10-6-3-7-15(18)21/h3-10,19-20,23-24H,11-14H2,1-2H3/t19-,20-,21-,22-/m1/s1
InChI Key	XSYCDVWYEVUDKQ-GXRSIYKFSA-N
Melting Point	245 °C
Purity	90%+
Storage	store at 2℃-8℃
Complexity	531
Covalently-Bonded Unit Count	1
Defined Atom Stereocenter Count	4
Exact Mass	346.21574685
Harmonized Tariff Code	Switzerland: 29339910 - USA: 2933999701 - Slovakia: 2933991000 - UK: 2933998000 - China: 2933990000
Heavy Atom Count	26
Hydrogen Bond Acceptor Count	4
Hydrogen Bond Donor Count	2
Isomeric SMILES	CN1CC[C@@]23[C@@H]4NC5=CC=CC=C5[C@@]2([C@@H]1NC6=CC=CC=C36)CCN4C
MDL Number	MFCD00010526
Monoisotopic Mass	346.21574685
PhysicalState	Powder
Rotatable Bond Count	0
Topological Polar Surface Area	30.5 Ų

Custom Q&A

What is the chemical name of the compound calycanthine?

The chemical name of the compound calycanthine is (4bS)-5,6,11,12-Tetrahydro-13,18-dimethyl-5β,10bβ:11β,4bβ-bis(iminoethano)dibenzo[c,h][2,6]naphthyridine.

What is the CAS number of calycanthine?

The CAS number of calycanthine is 595-05-1.

What is the molecular formula of calycanthine?

The molecular formula of calycanthine is C22H26N4.

What are the synonyms of calycanthine?

The synonyms of calycanthine include (+)-Calycanthine and 5,10b:11,4b-Bis(iminoethano)dibenzo[c,h][2,6]naphthyridine.

What is the melting point of calycanthine?

The melting point of calycanthine is 245° (evac tube).

How is calycanthine solubility in chloroform and methanol?

Calycanthine is slightly soluble in chloroform and methanol.

What is the form of calycanthine?

Calycanthine is in the form of a white to pale brown solid.

From which plant is calycanthine isolated?

Calycanthine is isolated from the stems and leaves of dried Palicourea alpina.

What is the main usage of calycanthine?

The main usage of calycanthine is as a bitter and poisonous crystalline alkaloid obtained from seeds of plants of the genus Calycanthus.

What is the family to which calycanthine belongs?

Calycanthine belongs to the family of Naphthyridines.

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