Cytochalasin D

Catalog Number	ACM22144770
CAS Number	22144-77-0
Structure
Synonyms	Zygosporin A
IUPAC Name	[(1R,2R,3E,5R,7S,9E,11R,12S,14S,15R,16S)-16-Benzyl-5,12-dihydroxy-5,7,14-trimethyl-13-methylidene-6,18-dioxo-17-azatricyclo[9.7.0.01,15]octadeca-3,9-dien-2-yl] acetate
Molecular Weight	507.62
Molecular Formula	C30H37NO6
Canonical SMILES	CC1CC=CC2C(C(=C)C(C3C2(C(C=CC(C1=O)(C)O)OC(=O)C)C(=O)NC3CC4=CC=CC=C4)C)O
InChI	InChI=1S/C30H37NO6/c1-17-10-9-13-22-26(33)19(3)18(2)25-23(16-21-11-7-6-8-12-21)31-28(35)30(22,25)24(37-20(4)32)14-15-29(5,36)27(17)34/h6-9,11-15,17-18,22-26,33,36H,3,10,16H2,1-2,4-5H3,(H,31,35)/b13-9+,15-14+/t17-,18+,22-,23-,24+,25-,26+,29+,30+/m0/s1
InChI Key	SDZRWUKZFQQKKV-JHADDHBZSA-N
Purity	95%+
Storage	Store in dry, low temperature, sealed, 2-8 °C.
Complexity	996
Exact Mass	507.26208790
Heavy Atom Count	37
Isomeric SMILES	C[C@H]1C/C=C/[C@H]2[C@@H](C(=C)[C@H]([C@@H]3[C@@]2([C@@H](/C=C/[C@@](C1=O)(C)O)OC(=O)C)C(=O)N[C@H]3CC4=CC=CC=C4)C)O
Monoisotopic Mass	507.26208790
Topological Polar Surface Area	113Ų

Custom Q&A

What is the molecular formula of Cytochalasin D?

The molecular formula of Cytochalasin D is C30H37NO6.

What is the melting point of Cytochalasin D?

The melting point of Cytochalasin D is 255-260°C.

How is Cytochalasin D stored?

Cytochalasin D is stable for 2 years from the date of purchase when stored at -20°C, and solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

What are the safety hazard codes associated with Cytochalasin D?

The hazard codes associated with Cytochalasin D are T.

How does Cytochalasin D act as an anti-hypertensive drug?

Cytochalasin D acts on human intestinal epithelial caco-2 cells and has activity in HMG-CoA reductase inhibitors used in the lowering of cholesterol.

What biological activity does Cytochalasin D exhibit?

Cytochalasin D is a potent disruptor of actin filament function and alters tight junction permeability.

What is the reactivity profile of Cytochalasin D?

Cytochalasin D may be sensitive to exposure to heat and can react with strong oxidizing agents, strong acids, and strong bases.

How does Cytochalasin D affect the cell cycle?

Cytochalasin D disrupts actin microfilaments and activates the p53-dependent pathways causing arrest of the cell cycle at the G1-S transition.

What is the general description of Cytochalasin D in terms of physical appearance?

Cytochalasin D appears as needles or fluffy white powder.

How is Cytochalasin D commonly used in cellular research?

Cytochalasin D is used as a cell cycle arresting compound in actin polymerization studies and cytological research.

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