Homatropine Hydrobromide

Catalog Number	ACM51569-2
CAS Number	51-56-9 / 87-00-3
Description	Natural alkaloid
Synonyms	Mandelyltropeine hydrobromide;Tropine mandelate hydrobromide;(1R,5S)-3-{[(2R)-2-hydroxy-2-phenylacetyl]oxy}-8-methyl-8-azoniabicyclo[3.2.1]octane;(±)-Homatropine bromide;1αH,5αH-Tropan-3α-ol, mandelate (ester), hydrobromide;8-Methyl-8-Azabicyclo[3.2.1]Oct-3-Yl Hydroxy(Phenyl)Acetate;8-Methyl-8-Azabicyclo[3.2.1]Oct-3-Yl Hydroxy(Phenyl)Acetate Hydrobromide (1:1);Benzeneacetic acid, α-hydroxy-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide;Benzeneacetic acid, α-hydroxy-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide (1:1)
Molecular Weight	356.26g/mol
Molecular Formula	C16H21NO3·HBr
Melting Point	212°C
Flash Point	212°C
Purity	>99.0%(T)
Appearance	White to Almost white powder to crystal
Storage	Room temperature (15-25°C)
Condition To Avoid	Light Sensitive
Degree Of Certification	Homatropine hydrobromide reference substance is a primary reference standard with certified absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities).
EC Number	200-105-3
Hazard Class	6.1
Hazard Excepted Quantities	E1 (Inner packaging: 30, Outer packaging: 1000)
Hazard Limited Quantities	5kg
Hazard Statements	H301+H311+H331: Toxic if swallowed. Toxic in contact with skin. Toxic if inhaled. P261: Avoid breathing dust, fumes, gas, mist, vapours, spray. [As modified by IV ATP]. P264: Wash thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. P301+P310+P330: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. Rinse mouth. P302+P352+P312: IF ON SKIN: Wash with plenty of soap and water. Call a POISON CENTER or doctor/physician if you feel unwell. P403+P233: Store in a well ventilated place. Keep container tightly closed.
HS Code	2939799090
MDL Number	MFCD00012676
Packing Group	III
Signal Word	Danger
UN Number	1544

Custom Q&A

What is the chemical formula of Homatropine Hydrobromide?

The chemical formula of Homatropine Hydrobromide is C16H22BrNO3.

What is the melting point of Homatropine Hydrobromide?

The melting point of Homatropine Hydrobromide is 214-217 °C.

What is the solubility of Homatropine Hydrobromide in water?

Homatropine Hydrobromide is soluble in water.

What is the main usage of Homatropine Hydrobromide?

Homatropine Hydrobromide is used as an anticholinergic agent, particularly in eye drops to induce mydriasis.

How does Homatropine Hydrobromide affect acetylcholine-induced contractions in muscle strips?

Homatropine Hydrobromide reduces acetylcholine-induced contractions of isolated muscle strips.

What brand name is Homatropine Hydrobromide available under?

Homatropine Hydrobromide is available under the brand name Isopto Homatropine.

What is the hazard class of Homatropine Hydrobromide?

The hazard class of Homatropine Hydrobromide is 6.1.

How is Homatropine Hydrobromide used clinically in the eye?

Homatropine Hydrobromide is used topically to paralyze the ciliary structure of the eye and to induce mydriasis.

How does Homatropine Hydrobromide differ from atropine in terms of action in the eye?

Homatropine Hydrobromide acts more rapidly but less persistently than atropine in the eye.

How can the action of Homatropine Hydrobromide be reversed quickly?

The action of Homatropine Hydrobromide can be reversed quickly by using a miotic, such as physostigmine, to restore the pupil to normality in a few hours.

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