Jatrorrhizine hydrochloride

Catalog Number	ACM2106804015
CAS Number	2106804-01-5
Structure
Description	Jatrorrhizine hydrochloride is a naturally occurring compound, which has been shown to have hypoglycemic effects and can be used for the treatment of skin cancer. It is an analogue of berberine that inhibits mitochondrial membrane potential, leading to cell death by inhibiting energy metabolism and causing chromatographic analysis. Jatrorrhizine hydrochloride also inhibits the synthesis of proteins required for glycolysis, including hexokinase 2 (HK2), phosphofructokinase 1 (PFK1), and pyruvate kinase M2 (PKM2). This drug is metabolized by esterases or glucuronidases to form benzalkonium chloride or ginsenoside RG3. This active form binds to penicillin-binding protein, which may lead to metabolic disorders such as hepatic steatosis.
Molecular Weight	374.84 g/mol
Molecular Formula	C20H20NO4·HCl
Canonical SMILES	COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)O)OC)OC.[Cl-]
Storage	store at 10℃-25℃
Harmonized Tariff Code	Switzerland: 29062910 - USA: 2906296000 - Slovakia: 2906290030 - UK: 2906290000 - China: 2906299909

Custom Q&A

What is the chemical formula for Jatrorrhizine hydrochloride?

The chemical formula for Jatrorrhizine hydrochloride is C20H21ClNO4+.

What are some synonyms for Jatrorrhizine hydrochloride?

Some synonyms for Jatrorrhizine hydrochloride include Dibenzo[a,g]quinolizinium, Neprotine chloride, and Yatrorhizine chloride.

What is the molecular weight of Jatrorrhizine hydrochloride?

The molecular weight of Jatrorrhizine hydrochloride is 374.84 g/mol.

What are some product categories that Jatrorrhizine hydrochloride falls under?

Jatrorrhizine hydrochloride falls under categories such as inhibitors, pharmaceutical intermediates, phytochemicals, and reference standards from Chinese medicinal herbs.

What are the chemical properties of Jatrorrhizine hydrochloride?

Jatrorrhizine hydrochloride is described as bright yellow needle crystals that are easily soluble in methanol. It is derived from various plants such as Phellodendron chinensis and coptis chinensis.

Which plant is Jatrorrhizine hydrochloride derived from?

Jatrorrhizine hydrochloride is derived from Phellodendron chinensis, green ox gall, palm leaf fangji root, golden fruit olive, and coptis chinensis.

What are some of the reported effects of Jatrorrhizine hydrochloride?

Jatrorrhizine hydrochloride has reported anti-gout, anti-tumor, and analgesic effects.

What is the color and solubility of Jatrorrhizine hydrochloride crystals?

Jatrorrhizine hydrochloride crystals are described as bright yellow and easily soluble in methanol.

What is the CAS number for Jatrorrhizine hydrochloride?

The CAS number for Jatrorrhizine hydrochloride is 960383-96-4.

What are some of the uses of Jatrorrhizine hydrochloride?

Some uses of Jatrorrhizine hydrochloride include its anti-gout, anti-tumor, and analgesic effects.

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