Lapatinib

Catalog Number	ACM231277922-1
CAS Number	231277-92-2
Structure
Synonyms	Lapatinib ditosylate
IUPAC Name	N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine
Molecular Weight	581.06
Molecular Formula	C29H26ClFN4O4S
Canonical SMILES	CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl
InChI	InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)
InChI Key	BCFGMOOMADDAQU-UHFFFAOYSA-N
Purity	98%+
Storage	Store in dry, low temperature, sealed, 2-8 °C.
Complexity	898
Exact Mass	580.1347324
Heavy Atom Count	40
Monoisotopic Mass	580.1347324
Topological Polar Surface Area	115Ų

Custom Q&A

What is the chemical formula of Lapatinib?

The chemical formula of Lapatinib is C29H26ClFN4O4S.

What is the melting point of Lapatinib?

The melting point of Lapatinib is 144-146°C.

What is the storage temperature recommended for Lapatinib?

The storage temperature recommended for Lapatinib is 2-8°C, protected from light.

What is the mechanism of action of Lapatinib?

Lapatinib is a tyrosine kinase inhibitor that can effectively inhibit the tyrosine kinase activity of human epidermal growth factor receptors 1 and 2 (ErbB1, ErbB2).

What is Lapatinib indicated for in terms of breast cancer treatment?

Lapatinib is indicated for use in combination with capecitabine for treating patients with advanced or metastatic breast cancer whose tumors overexpress HER2.

What is Lapatinib's brand name?

Lapatinib's brand name is Tykerb.

What type of cancer is Lapatinib specifically effective against?

Lapatinib is specifically effective against breast cancer.

How does Lapatinib work in breast cancer treatment?

Lapatinib can act simultaneously on both Her-1 and Her-2 receptors, inhibiting the proliferation and growth of tumor cells.

What is Lapatinib's role in breast cancer research?

Lapatinib is used as an antineoplastic agent and a tyrosine kinase inhibitor in breast cancer research.

What is Lapatinib's target in the body?

Lapatinib's target in the body is the EGFR and ErbB2 receptors.

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