Lycopsamine

Catalog Number	ACM10285071-1
CAS Number	10285-07-1
Structure
Description	Lycopsamine is a linear polyamine that is structurally related to the neurotransmitter serotonin. It is a potent inhibitor of bacterial growth, and it has been shown to inhibit transcription-quantitative polymerase chain reaction (PCR) in rat liver microsomes. Lycopsamine also inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Lycopsamine also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.
Molecular Weight	299.36 g/mol
Molecular Formula	C15H25NO5
Canonical SMILES	C[C@@H]([C@@](C(C)C)(C(=O)OCC1=CCN2[C@H]1[C@@H](CC2)O)O)O
Storage	store at <-15℃, close container well
Harmonized Tariff Code	Switzerland: 29397900 - USA: 2939790000 - Slovakia: 2939799090 - UK: 2939799090 - China: 2939799099
MDL Number	MFCD09260181

Custom Q&A

What is the chemical formula for Lycopsamine?

Lycopsamine has a chemical formula of C15H25NO5.

What is the melting point of Lycopsamine?

The melting point of Lycopsamine is 41-44°C.

What is the boiling point of Lycopsamine?

The predicted boiling point of Lycopsamine is 463.3±45.0 °C.

In what types of solvents is Lycopsamine soluble?

Lycopsamine is soluble in chloroform and ethanol.

What is the storage temperature recommended for Lycopsamine?

Lycopsamine should be stored at -20°C.

From which plant species has Lycopsamine been isolated?

Lycopsamine has been isolated from Arnsinckia hispida, A. interrnedia, and A. lycopsoides.

What are the known effects of pyrrolizidine alkaloid-containing plants, such as Lycopsamine, on livestock, wildlife, and humans?

Pyrrolizidine alkaloid-containing plants are known as hepatotoxins and tumorigens, affecting livestock, wildlife, and humans.

What biological biomarker of pyrrolizidine alkaloid-induced liver tumor formation has been identified?

Pyrrolizidine Alkaloid-Derived DNA Adducts have been identified as the common biological biomarker of pyrrolizidine alkaloid-induced liver tumor formation.

What is the general description of Lycopsamine as a primary reference substance?

Lycopsamine is described as a primary reference substance with assigned absolute purity, considering chromatographic purity, water, residual solvents, and inorganic impurities.

What is the producer of Lycopsamine as a primary reference substance?

Lycopsamine as a primary reference substance is produced by PhytoLab GmbH & Co. KG.

※ Please kindly note that our products are for research use only.