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Catalog Number | ACM2188683-1 |
CAS Number | 2188-68-3 |
Description | Lycorine HCl is a natural compound that is an amide of the alkaloid lycorine. It has been shown to inhibit protein synthesis and may also act as a proton pump inhibitor. Lycorine HCl has been found to have antiviral activity and may be useful for the treatment of hepatitis, cancer, and other diseases. Lycorine HCl has been shown to be stereoselective, meaning it will only bind to one enantiomer of the enzyme it targets. It binds to the amide group of acetylcholinesterase in order to inhibit its activity and stop the breakdown of acetylcholine in the brain. This allows for better transmission of nerve impulses across synapses, which can lead to improved memory function. |
Molecular Weight | 323.77 g/mol |
Molecular Formula | C16H17NO4HCl |
Canonical SMILES | C1CN2CC3=CC4=C(C=C3[C@H]5[C@H]2C1=C[C@@H]([C@H]5O)O)OCO4.Cl |
Storage | store at 2℃-8℃ |
Harmonized Tariff Code | Switzerland: 29397900 - USA: 2939790000 - Slovakia: 2939791000 - UK: 2939490000 - China: 2939799091 |
MDL Number | MFCD00243111 |
What is the chemical formula of Lycorine?
The chemical formula of Lycorine is C16H17NO4.
What is the melting point of Lycorine?
The melting point of Lycorine is 253-255℃ (dec.).
In which solvents is Lycorine soluble?
Lycorine is soluble in Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
What is the main active ingredient extracted from Lycorine herbs?
The main active ingredients extracted from Lycorine herbs are about 40 alkaloids, with galanthamine, lycorine, lycoramine, lycorenine, and crinine being the major effective medicinal ingredients.
What is the pharmacological effect of Lycorine on the central nervous system?
Lycorine can accelerate conditioned reflexes of motor and defense nature in mice, resulting in a good sedative effect.
How is Lycorine used in the treatment of diseases?
Lycorine may be used to treat amebic dysentery and against cancer.
What are some of the other effects of Lycorine?
Lycorine has an antiparasitic and anti-malaria effect, anti-inflammatory effect, emetic effect, and also shows antitumor activity.
How is Lycorine commonly extracted?
Lycorine is commonly extracted using the solvent extraction method, chromatographic separation, and resin absorption.
What are the safety statements associated with Lycorine?
The hazard code associated with Lycorine is T, and the risk statement is 25.
What is the pharmacological indication and dosage for the injection of Lycorine?
The pharmacological indication for injection of Lycorine is resistance to amebic protozoa and treatment of intraintestinal/extraintestinal amebiasis. The subcutaneous injection dosage is 25-50 mg/injection and 50 mg/day.
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