Protoveratrine

Catalog Number	ACM143577
CAS Number	143-57-7
Structure
Description	Protoveratrine is an alkaloid that is found in the seeds of the red kidney bean. It has been shown to have a wide range of biological properties and can be used as an experimental model for congestive heart failure. Protoveratrine has also been shown to inhibit sodium citrate-induced hypernatremia and lc-ms/ms method, which is an analytical method for the quantification of human serum proteins. This compound also inhibits the expression of protein genes involved in energy metabolism, such as ATP synthase and pyruvate dehydrogenase kinase 4. Protoveratrine has been shown to be effective against autoimmune diseases, such as lupus erythematosus, which are caused by autoantibodies that attack the body's own cells.
Synonyms	Protoveratrine A
Molecular Weight	793.94 g/mol
Molecular Formula	C41H63NO14
Canonical SMILES	CC[C@@H](C)C(=O)O[C@H]1[C@@H]([C@H]2[C@@H](CN3C[C@H](CC[C@H]3[C@@]2(C)O)C)[C@H]4[C@@]1([C@@H]5[C@@H]([C@@H]([C@H]6[C@]7([C@]5(C4)O[C@@]6([C@H](CC7)OC(=O)[C@](C)(CC)O)O)C)OC(=O)C)OC(=O)C)O)O
Storage	store at 2℃-8℃, close container well
Harmonized Tariff Code	Switzerland: 29397900 - USA: 2939790000 - Slovakia: 2939799090 - UK: 2939799090 - China: 2939799099
MDL Number	MFCD00135586

Custom Q&A

What is the chemical formula of Protoveratrine A+B?

The chemical formula of Protoveratrine A+B is C82H126N2O29.

What is the molecular weight of Protoveratrine A+B?

The molecular weight of Protoveratrine A+B is 1603.87.

What is the melting point of Protoveratrine A+B?

The melting point of Protoveratrine A+B is 275-283°C.

How was Protoveratrine A+B first isolated?

Protoveratrine A+B was first isolated by Salzberger and reexamined by Poethke.

What color does the alkaloid Protoveratrine A+B give when dissolved in H2SO4 and heated?

Protoveratrine A+B gives a blue color that changes to violet when dissolved in H2SO4 and heated.

What is the color of Protoveratrine A+B when dissolved in HCl and H3PO4?

The color of Protoveratrine A+B is cherry-red when dissolved in HCl and H3PO4.

What acids are yielded when Protoveratrine A+B undergoes alkaline hydrolysis?

Protoververatine A+B yields protoverine, acetic, methylethylacetic, and methylethylglycollic acids.

What is the main medicinal use of Protoveratrine A+B?

Protoveratrine A+B is used as a medicine to lower blood pressure.

How is Protoveratrine A+B defined as a substance?

Protoveratrine A+B is defined as a substance isolated from the Veratrum album plant, being a mixture of two alkaloids - protoveratrine A and protoveratrine B.

What is the brand name for Protoveratrine A+B?

The brand name for Protoveratrine A+B is Protalba (Marion Merrell Dow).

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