Seneciphylline

Catalog Number	ACM480819
CAS Number	480-81-9
Description	Seneciphylline is a naturally occurring alkaloid that has been identified in the leaves of the plant Senecio longilobus. It is an autophagy inducer and has been shown to potentiate the effects of matrix metalloproteinase (MMP) and to modulate the activity of mitochondrial enzymes. This alkaloid also induces apoptosis in murine sarcoma virus-infected cells. Seneciphylline has been found to be a genotoxic agent, with evidence for its genotoxic activity being observed in various studies. The long-term toxicity and toxicological studies on seneciphylline have not yet been conducted.
Molecular Weight	333.38 g/mol
Molecular Formula	C18H23NO5
Canonical SMILES	C/C=C\1/CC(=C)[C@@](C(=O)OCC2=CCN3[C@H]2[C@@H](CC3)OC1=O)(C)O
Storage	store at 2℃-8℃, keep under inert gas: Nitrogen, protect from light
Harmonized Tariff Code	Switzerland: 29397900 - USA: 2939790000 - Slovakia: 2939799090 - UK: 2939799090 - China: 2939799099
MDL Number	MFCD00221722

Custom Q&A

What is another name for Seneciphylline?

ALPHA-LONGILOBINE, SENECPHYLLIN, (15cis)-12-Hydroxy-13,19-didehydrosenecionan-11,16-dione, etc.

What is the chemical formula for Seneciphylline?

C18H23NO5

What is the melting point of Seneciphylline?

217°C

In what solvents is Seneciphylline soluble?

Seneciphylline is soluble in DMF, DMSO, ethanol, and PBS (pH 7.2).

What is the potential hazardous classification of Seneciphylline?

Hazardous substance, Hazard Class 6.1(b), Packing Group III

How is Seneciphylline derived?

Seneciphylline is derived from the whole plant or root of Gynura segetum (Lour.) Merr (Ju Sanqi).

What are some uses of Seneciphylline?

It has the effect of coagulation and hemostasis, and it is used as a plant toxin to defend against herbivore and insect attacks.

What are some safety risks associated with Seneciphylline?

Hazard Codes T, Risk Statements 23/24/25-25, Safety Statements 1-20-24/25-45

What is the hazard class and Packing Group of Seneciphylline according to WGK Germany?

Hazard Class 6.1(b), Packing Group III

What are some symptoms associated with Seneciphylline exposure?

Symptoms include abdominal pain, nausea and diarrhea, emaciation, intestinal edema, and liver congestion.

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