Toddalin

Catalog Number	ACM3895929-1
CAS Number	3895-92-9
Description	Toddalin is a natural compound that is extracted from the leaves of Toddalia asiatica. It has been shown to inhibit the proliferation of certain types of cancer cells, including squamous carcinoma, through inhibition of protein synthesis. Toddalin is a basic protein with a molecular weight of around 4,000 Da, which can be found in both plants and animals. The physiological levels are unknown. This extract has been shown to have biological properties such as the ability to inhibit kinase activity and block adenosine receptors A3 (AR). It also inhibits cell factor-mediated activation of transcriptional factors such as NF-κB, AP-1, or p38 MAPK. Further research on this compound is needed to determine its effects on human health and ecological systems.
Synonyms	Chelerythrine chloride
Molecular Weight	383.82 g/mol
Molecular Formula	C21H18ClNO4
Canonical SMILES	C[N+]1=C2C(=C3C=CC(=C(C3=C1)OC)OC)C=CC4=CC5=C(C=C42)OCO5.[Cl-]
Storage	store at <-15℃
Harmonized Tariff Code	Switzerland: 29397900 - USA: 2939790000 - Slovakia: 2939791000 - UK: 2939490000 - China: 2939799091
MDL Number	MFCD00060717

Custom Q&A

What is the chemical formula for Chelerythrine Chloride?

The chemical formula for Chelerythrine Chloride is C21H18ClNO4.

What are some synonyms for Chelerythrine Chloride?

Some synonyms for Chelerythrine Chloride are TODDALIN, TODDALIN CHLORIDE, and CHELERYTHIN CL.

What is the melting point of Chelerythrine Chloride?

The melting point of Chelerythrine Chloride is 195-205°C.

What is the solubility of Chelerythrine Chloride in DMSO?

Chelerythrine Chloride has a solubility of ≥10 mg/mL in DMSO.

What is the color of pure Chelerythrine Chloride?

Pure Chelerythrine Chloride is yellow to orange in color.

How should Chelerythrine Chloride be stored?

Chelerythrine Chloride should be stored in an inert atmosphere, in a freezer, under -20°C.

What is the primary usage of Chelerythrine Chloride?

Chelerythrine Chloride is primarily used as a cell-permeable protein kinase C (PKC) inhibitor.

What are the safety hazard codes associated with Chelerythrine Chloride?

The safety hazard codes associated with Chelerythrine Chloride are Xn and Xi.

How does Chelerythrine Chloride induce apoptosis in cancer cells?

Chelerythrine Chloride induces apoptosis in cancer cells by inhibiting Bcl-xL function and displacing Bax binding.

What are some of the physiological actions of Chelerythrine Chloride?

Chelerythrine Chloride is known to activate p38 MAP kinase and JUNK signaling pathways, as well as inhibiting protein kinase C and inducing apoptosis in cancer cells.

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